Level: BSc, MSci
Title: The basic reproduction number and heterogeneity in contact rates
Supervisor:
Research Area: Probability and Applications [Including Statistics]
Description:

The dynamics of infectious disease transmission are often modelled using a system of ordinary differential equations. An important summary quantity that can be calculated for this kind of model is the basic reproduction number, R_0. This is defined as the average number of onward infections that a typical infected individual produces, and an infection can invade a population if and only if R_0 is greater than 1. It often happens that there is variation in contact rates, e.g. for insect-borne infections, some people are bitten much more than others. This project would first review how R_0 is calculated in the general case, and then how variation in contact rates changes R_0. The student may implement one or more types of model to numerically verify the behaviour.

Further Reading:
  • O. Diekmann, J. Heesterbeek, Mathematical epidemiology of infectious diseases. Wiley, Chichester, 2000.

  • C. Dye, G. Hasibeder, Population dynamics of mosquito-borne disease: effects of flies which bite some people more frequently than others, Transactions of the Royal Society of Tropical Medicine and Hygiene 80 1 (1986): 69–77.

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Current Availability: Yes