This module introduces the Drug Discovery process and the action of medicinal drugs. It is an integral part of the degree programs in Pharmaceutical Chemistry. Topics covered include identifying drug targets such as receptors and enzymes, drug-target interactions, hit identification and lead optimization. We will also discuss the use of computers in medicinal chemistry. Structure-activity relationships will be explored before biological assays and concentration-response relationships are discussed. Finally, we will look at drug disposition, pharmacokinetics (including ADME) and how to get a drug to the market.